North Wilkesboro is a very small town located in the state of North Carolina. With a population of 4,280 people and five associated neighborhoods, North Wilkesboro is the 188th largest community in North Carolina.

One interesting thing about the economy is that relatively large numbers of people worked from their home: 11.81% of the workforce. While this number may seem small overall, as a fraction of the total workforce this is high compared to the rest of the county. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

As is often the case in a small town, North Wilkesboro doesn't have a public transportation system that people use for their commute.

The overall education level of North Wilkesboro is somewhat higher than in the average US city of 21.84%: 26.10% of adults 25 and older in the town have at least a bachelor's degree.

The per capita income in North Wilkesboro in 2022 was $31,753, which is upper middle income relative to North Carolina, and middle income relative to the rest of the US. This equates to an annual income of $127,012 for a family of four. However, North Wilkesboro contains both very wealthy and poor people as well.

North Wilkesboro is a very ethnically-diverse town. The people who call North Wilkesboro home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of North Wilkesboro residents report their race to be White, followed by Black or African-American. Important ancestries of people in North Wilkesboro include English, German, Irish, Scottish, and Scots-Irish.

The most common language spoken in North Wilkesboro is English. Other important languages spoken here include Spanish and Italian.