Thonotosassa is a medium-sized town located in the state of Florida. With a population of 15,238 people and seven associated neighborhoods, Thonotosassa is the 171st largest community in Florida.

Telecommuters are a relatively large percentage of the workforce: 14.19% of people work from home. While this number may seem small overall, as a fraction of the total workforce it is high relative to the nation. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

The education level of Thonotosassa citizens is a little higher than the average for US cities and towns: 24.29% of adults in Thonotosassa have at least a bachelor's degree.

The per capita income in Thonotosassa in 2022 was $33,418, which is middle income relative to Florida and the nation. This equates to an annual income of $133,672 for a family of four. However, Thonotosassa contains both very wealthy and poor people as well.

Thonotosassa is an extremely ethnically-diverse town. The people who call Thonotosassa home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Thonotosassa residents report their race to be White, followed by Black or African-American. Thonotosassa also has a sizeable Hispanic population (people of Hispanic origin can be of any race). People of Hispanic or Latino origin account for 13.40% of the town’s residents. Important ancestries of people in Thonotosassa include German, Irish, English, Italian, and French.

The most common language spoken in Thonotosassa is English. Other important languages spoken here include Spanish and Arabic.